Thank you for contacting Mearto with your appraisal inquiry.

It is a beautiful vintage Louis Vuitton travel bag. Such vintage designer accesssories are being offered at auction on a regular basis.
The Louis Vuitton bag is made of the beautiful classic logo material, from the photos it appears to have some signs of wear and use. This both adds to the charm and look however it also decreases the value slightly as collectors and dealers tend to prefer items that are in mint and unused condition. The fact that you do not have the original receipt and the dustbag also decreases the value as this would be an easy proof of authenticity. However the details on the bag more than indicate that it is a genuine Louis Vuitton overnight bag.

I believe that the bag would attract the attention of both collectors and dealers if it came up for auction due to its lovely vintage shape and charming patina.
The estimate provided is for a well-advertised specialised online designer accessories auction, where I believe the overnight bag has the best chance of realising its fullest potential. However, there is no measurement for the sentimental value you might attach to your grandmother's Louis Vuitton bag. Retail "asking prices" can be higher and vary.

Please let me know if you have any additional questions. I’m happy to help.
Thank you