Thank you for submitting your item for appraisal. This appears to be a japanse woodblock print by Utagawa Yoshitsuna, : Inshoku yôjô kagami. The inner workings of the body while eating and drinking. Signed: Ittôsai Yoshitsuna ga. Publisher: Mikawaya Tetsugorô. Censor: aratame. Date: 9/1855. (There is also a female part to it) Just the male version sells in the price range listed at auction. You may find much higher prices in the trade. The print in your possession shows creases from folding which would not allow a higher estimate.